Thirty-two years ago Ginger Gray walked into her doctor’s office complaining of abdominal pain, diarrhea, severe weight loss, and overwhelming joint pain. At 19, she hadn’t grown an inch since the sixth grade. But her doctor said there was nothing physically wrong with her, and even suggested she seek psychiatric counseling.

Fortunately for Gray, she sought another physician’s opinion.

Based on tests he conducted, the doctor recommended the 4-foot-11-inch Pennsylvania resident begin full-time treatment for Crohn’s disease.”Crohn’s disease robbed me of my stamina,” Gray says. “It took two years for me to fully regain my strength and weight so that I could begin working again.”Until now, treatment for Crohn’s has relied on surgery and anti-inflammatory and other drugs also used to treat other conditions.

In August 1998, the Food and Drug Administration licensed the first treatment specifically for Crohn’s disease, an incurable and sometimes debilitating inflammation of the bowel.Remicade (infliximab) is a genetically engineered antibody that blocks inflammation caused by a protein called tumor necrosis factor. After clinical trials showed benefit from Remicade treatment within a two-to-four week period following a single dose, FDA approved the drug for patients with moderate to severe Crohn’s disease who have not found relief with other treatments.

“We recognized that [Remicade] had such a dramatic effect on patients,” says Barbara Matthews, M.D., a medical officer in FDA’s Center for Biologics Evaluation and Research, “that it was given accelerated approval.”Remicade, which is taken intravenously, can decrease the amount of inflammation along the lining of the intestine.

Clinical trials also show that Remicade is effective in closing fistulas (abnormal passages or sores between the bowel and skin). Although not a cure, the drug reduces the symptoms in patients who have not responded well to traditional treatments.”This is an exciting development for two reasons,” says R. Balfour Sartor, M.D., professor of medicine, microbiology and immunology at the University of North Carolina, and chairman of the National Scientific Advisory Committee for the Crohn’s & Colitis Foundation of America (CCFA). “It is the first therapy for Crohn’s disease derived by molecular techniques, and it has the possibility of improving the quality of life for [Crohn's] patients.”

But Sartor also cautions that the long-term toxic effects of Remicade are unknown and that the drug is not needed by every Crohn’s disease patient. “Two-thirds of the people will have near immediate results,” he says, “but only those patients who do not respond to other therapies” are eligible to take the drug. The next step is to maintain a patient’s remission after the drug’s initial effect has worn off.

Currently, studies are being done to better define the risks and longer-term benefits of Remicade because drug reactions and potential adverse effects from suppressing tumor necrosis factor require further clarification. Crohn’s disease is one of two major types of inflammatory bowel diseases (IBD)–the general term for diseases that cause inflammation in the intestines–and has no cure and a high rate of recurrence following treatment.

It usually occurs in the lowest portion of the small intestine (ileum), and the large intestine (colon or bowel), but it can occur in other parts of the digestive tract. Crohn’s usually involves all layers of the intestinal wall.

The disease can be difficult to diagnose because its symptoms, which include chronic diarrhea, crampy abdominal pain, loss of appetite, and weight loss, often mimic those of the other IBD type–ulcerative colitis–which affects only the colon. (See “Is It Crohn’s Disease?”)

Crohn’s disease is a condition where there is inflammation in the gut. The disease flares up from time to time. Symptoms vary, depending on the part of the gut affected. Medication can often ease symptoms when they flare-up. Surgery to remove sections of the gut is needed to treat some flare-ups. Medication taken each day may prevent symptoms from flaring-up.

IF YOU HAVE Crohn’s disease, you probably already know the bad news: The illness is incurable. If you’re a vegetarian with Crohn’s, the news is even more distressing: The standard medical solution often includes eating meat. Fortunately, though, there is hope. Natural medicine can help you control this potentially debilitating condition, in many cases without becoming a meat eater.

PATRICK DONOVAN, N.D., a naturopathic physician in private practice as well as a professor of gastroenterology at Bastyr University of Natural Health Sciences in Seattle, has seen several dozen cases of Crohn’s disease in the past 10 years. Donovan is quick to point out that allopathic medicine plays an important role in managing the disease. “There’s a place for prednisone and hospitalization when treating Crohn’s,” says Donovan. “A person can die from this disease, especially during a flare-up. Conventional treatments can save lives.”

In fact, Donovan will treat only those Crohn’s patients who are also seeing a physician with hospital privileges. He also stresses the need for a correct diagnosis. He recently saw a patient who had been treated unsuccessfully for Crohn’s for 10 years; he determined that she in fact had celiac disease, a condition in which gluten, a protein found in various grains, damages the intestinal lining. Crohn’s disease cannot be prevented but you can reduce your symptoms. We know living with Crohn’s disease or ulcerative colitis can be difficult, but the right resources and support can make day-to-day living easier.

Crohn’s Disease is not normally fatal, however complications from the disease could be fatal if not seen to. These could be due to infection. Such as a perforated bowel if medical attention to it is not sought out quickly enough. About 1 in 1500 people have Crohn’s disease. It can develop at any age but most commonly starts between the ages of 15 and 40. It affects women slightly more often than men. The myth was created by the medical system to allow them to profit from those who are chronically ill. The cause and cure remain perpetually just beyond reach.

All they need is more money to keep looking. The elusive search for the cause and cure for Crohn’s disease is as futile as the elusive search for the cause and cure for Multiple Sclerosis. There is no need to search any further than the word toxicity, the one place the medical profession never looks. That is the smoking gun.

Look where they are not looking and you’ll find it. I was struck down by Crohn’s disease in the summer of 1993 when I was 44. I nearly died in 1994. I believe the name of an illness should help the person who has it to understand what he or she has, not to disguise the nature of the illness, which is what disease names usually do. Crohn was the name of the doctor who observed and described the disease. He gave his name to it. But, unfortunately, the word Crohn explains absolutely nothing about the nature of the condition.

It merely tells us the name of the person who claimed it for his own and, like Alzheimer and Parkinson and Hodgkin and so many other disease names. Disease naming actually keeps us in the dark. In my opinion, Crohn’s disease is caused by toxicity. In my case the intestines were poisoned by mercury leaching into the digestive tract from my mercury fillings. The body eliminates mercury extremely slowly. Chelation is the only way to effectively remove mercury at a rate that will allow the body to recover from disease. 90% of the mercury that is excreted from the body is eliminated through the intestines. When it is not eliminated quickly via chelation it is allowed to accumulate in the intestines where it causes tissues to become diseased through mercury poisoning. Mercury destroys the tissues and attracts parasites, unfriendly bacteria and fungus which contribute to toxicity in the intestines.

In my opinion, it would be more helpful if Crohn’s disease were called Toxic Intestinal Disease (TID). It is not easy to understand “we don’t know the cause, we don’t have a cure”, so we’ll name it after Dr. Crohn. But it is very easy to understand the word toxicity. Toxicity means poisoning.