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Posts Tagged ‘Persistent Diarrhea’
What is Colitis
Colitis is a general term for a large number of causes that result in inflammation in the lining of the bowel. Common symptoms associated with colitis are abdominal cramping, frequent loose stools or persistent diarrhea, loss of control of bowel function, fever, sleepiness, and weight loss.
Depending on the cause, colitis may be treated in several ways.One of the first steps in diagnosing colitis is identifying the cause. Some forms of colitis may be caused by infection through bacteria, certain viruses, and some parasites.
For example, exposure to the salmonella bacteria or any other bacteria needs to be treated with antibiotics to resolve the condition. Parasitic or amoebic infection usually warrants a course of either antibiotics or anti-parasitic medication. Viral colitis can be more difficult to treat.
Viruses like Rotavirus or Norovirus can result in dehydration, particularly in the very young or very old. Rest and increased fluid intake are often prescribed. However, if a person becomes severely dehydrated, he or she may need care in a hospital to receive intravenous fluids.
Certain diseases can predispose one to attacks of colitis. The most frequent cause of colitis in those with intestinal diseases is Crohn’s disease, which is a degenerative intestinal disorder. People with Crohn’s are more prone to colitis and to other serious conditions like perforated bowel.
Those with Crohn’s need to take seriously the symptoms listed above and see a doctor immediately. Any of these symptoms can necessitate medical treatment.Irritable bowel disorder (IB) can also cause bouts of colitis.
Since IB is both difficult to diagnose and to treat, anyone who has had frequent recurrences of the symptoms above is prone to colitis and should contact a doctor if he or she suspects colitis. Especially if bacteria or parasites causes the colitis, this can only worsen IB and needs immediate treatment.
While antibiotics are used to treat bacterial colitis, they can also be indicated as a cause of colitis in some cases. Additional causes of colitis may include taking birth control medication, having autoimmune disorders, or smoking.
If diarrhea and fever persist for more than two days, and you don’t have a disease that would necessitate earlier treatment, you should see a doctor quickly. If you have severe stomach pain with fever, you should not wait to see a physician during office hours but proceed to the emergency room, as this may indicate appendicitis or bowel injury.
If you suspect food poisoning, it is better to go the emergency room, since some bacteria can be very harmful.You can reduce your risk of colitis by using sanitary cooking and eating practices, avoiding caffeinated beverages, and not taking medications like ibuprofen if you have irritable bowel or inflammatory bowel conditions.
Treatment for those with frequent bouts of colitis will focus on trying to reduce symptoms such as diarrhea and stomach cramping. Sometimes these treatments of symptoms are the only way to address colitis.
Yet even with treatment, those with Crohn’s and other autoimmune or known stomach disorders should be vigilant if they suspect colitis, since other more serious conditions may also have the same symptoms as colitis.
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Can Viagra Help Crohns Disease
While well known for its effect on blood flow, until now Viagra has not been used to boost circulation in the intestine. That could change with the finding that Viagra can help treat Crohns disease. People with the long-term, inflammatory condition develop holes and ulcers in the intestine.
A team from University College London wondered whether an overactive immune reaction was the problem.The team carried out biopsies on six Crohns disease patients and nine healthy volunteers. The operation triggered an acute immune response in the healthy people, producing white blood cells to heal damage caused by the removal of cells. But the Crohn’s patients responded by producing far lower amounts of white blood cells. The researchers used Viagra to boost blood flow to the intestine in the patients with Crohns disease, thus increasing the flow of white cells to the damaged area.
Researchers in the U.K. have a new theory to explain the cause of Crohns disease, and they say medications like the erectile dysfunction drug Viagra may prove useful for treating the bowel disorder if they are right.In Crohns disease, chronic inflammation causes ulcers within the digestive tract that can lead to severe gastrointestinal symptoms, including abdominal pain, persistent diarrhea, and rectal bleeding.The most widely accepted theory is that an overactive immune system causes the damaging inflammation.
But researchers from the University College London say the opposite appears to be true.They believe a weaker-than-normal immune response triggers the bowel inflammation that leads to Crohns disease. The researchers tested this theory by treating 10 Crohn’s patients with 50 milligrams of Viagra after injecting them with the killed gut bacteria. They found that blood flow to the infected area improved.
“Increasing blood flow is an important part of the inflammatory response, and that is why this drug may work,” Segal says. “But we don’t yet know if this will give rise to successful treatment. We need to study this further to find out.” The disease usually affects the small intestine and one in every thousand people in the UK is afflicted with this miserable complaint.
But now scientists believe they have found the cause of Crohns disease, and they think it could be treated with Viagra.The team of researchers from University College London say they believe the cause is the opposite of what has been supposed and is triggered by a weak immune system, rather than an overactive one where cells are attacked by the body’s own immune system.
Crohn’s was previously thought to be an auto-immune disease and was treated with immuno-suppressant drugs. But the researchers led by Anthony Segal and colleagues have discovered that people with Crohn’s have a weak and unresponsive immune system which does not repair damage easily. They say the flow of blood to damaged cells is substantially reduced, and a drug such as Viagra, best known for its effects on erectile dysfunction, could help the healing process as it stimulates blood flow.
Since it was identified in the 1920s there have been many theories as to the cause of Crohn’s and it was often compared with tuberculosis, but attempts to find an infectious agent have failed.
The research team compared the immune system response of Crohn’s patients and healthy individuals to minor injuries, such as skin abrasions and discovered a difference in the number of white blood cells called neutrophils produced by the body to heal the damage in the bowel and on the surface of the skin.
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